Lithium-ion batteries are popular energy storage devices for a wide variety of applications. As batteries have transitioned from being used in portable electronics to being used in longer lifetime and more s. ••We develop a failure modes, mechanisms, and effects analysis of Li-ion b. Lithium-ion battery technology was first commercialized in 1991, and is successful due to its high energy density, high operating voltage, and low self-discharge rate. Application. FMMEA is “a systematic methodology to identify potential failure mechanisms and models for all potential failure modes, and to prioritize failure mechanisms” and is the cornerstone. Lithium-ion batteries are complex systems that undergo many different degradation mechanisms, each of which individually and in combination can lead to performance degradation, failu. The authors would like to thank the more than 150 companies and organizations that support research activities at the Center for Advanced Life Cycle Engineering (CALCE) at the University.